What can be meaningfully said of the unobserved world?

What can be meaningfully said of the unobserved world? Are states of mind and nature mostly determined or undetermined? How do your answers advance a resolution to the realism/anti-realism conflict?Sources to be used include “God does not play dice” – Einstein”Does God play Dice” -Hawking”Why God plays dice” -Buchanan””Is the real world really real” -Simanek