What forces propelled the debate on alcohol and drug use in the US in the late 1800s and early 1900s?

Just answer these questions: The Prohibition movement culminated with the ratification of the 18th Amendment in 1919. What forces propelled the debate on alcohol and drug use in the US in the late 1800s and early 1900s? Was Prohibition a success or failure? How do issues of alcohol and drug use affect the United States today?