Describe two historical events that have influenced the development of ethical codes and regulations for nursing and healthcare research.
Explain how each event has impacted ethical codes and regulations.

Part 1: Ethical Safeguards Describe why ethical safeguards designed for clinical research may not be feasible or appropriate for evidence-based practice or evidence-based practice implementation projects.

Part 2: Ethical Controversies Review the sectioned headed, Two Ethical Exemplars in Chapter 22 of the textbook (Melnyk and Fineout-Overholt, 2015, pages 518-519).

Discuss three main ethical controversies related to implementing Evidence-Based Quality Improvement (EBQI) Initiatives.
Describe how these controversies relate to the four core ethical principles. (Be sure to be clear which ethical principle you are addressing and note all four).
Part 3: Patients Responsibilities

Identify which ethical principles may be in conflict with the concept of “patients having an ethical responsibility in improving healthcare.”
Discuss how these conflicts may be resolved.