1. Explain the anatomic location and functions of the organ systems involved in the disorder/disease.
2. Describe how the pathology (what has gone wrong with the body) impacts on normal physiology, that is, what has caused the signs and symptoms.
3. Discuss how hormones and/or other cell signalling factors are dysregulated in the pathogenesis of the disorder/disease*.
4. Discuss how the disorder/disease is diagnosed and how it could be treated (using examples of current and novel approaches)*.

