1. Write a little bit of autoimmunity and lupus (SLE) 2. The most of the introduction should be about TROVE2 and antibodies that bound to TROVE2. Background about the TROVE2 protein, the gene, the transcript variants can get from it (It is important to write about the 5-prime ASS transcript variant ), and then the antibodies (autoantibodies and commercial antibodies). The autoantibodies where they bind (because you will find that some autoantibodies when you detect from people have systemic lupus, they bind to a different area that the ones have Sjogren syndrome .